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IGF-1 LR3 1mg
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Growth-Factor Signaling Research
IGF-1 LR3 1mg — Long R3 IGF-1 Research Peptide
IGF-1 LR3 1mg, also known as Long R3 IGF-1, is a modified analog of insulin-like growth factor 1 developed for experimental research involving IGF-1 receptor signaling, cellular growth pathways, metabolism and growth-factor biology. Its modified structure distinguishes it from endogenous IGF-1 and makes it a widely recognized compound in laboratory growth-factor research.
Compound
IGF-1 LR3
Content
1mg
Common Name
Long R3 IGF-1
Research Target
IGF-1 Receptor
What Is IGF-1 LR3?
IGF-1 LR3 is a modified analog of insulin-like growth factor 1 (IGF-1), an endogenous signaling molecule involved in growth-factor biology.
The abbreviation LR3 refers to Long R3. The molecule differs structurally from native IGF-1 through an amino-acid substitution at position 3 together with an additional N-terminal peptide extension.
These structural modifications alter the molecule's interaction with IGF-binding proteins while retaining its relevance to IGF-1 receptor (IGF1R) signaling research.
This makes IGF-1 LR3 useful in experimental systems designed to investigate growth-factor receptor activation, intracellular signaling and cellular responses under controlled laboratory conditions.
Structural Research
IGF-1 LR3 vs Native IGF-1
IGF-1 LR3 should not be confused with unmodified endogenous IGF-1. Although the molecules are closely related, LR3 was engineered with structural changes that affect its biochemical behavior.
Native Molecule
IGF-1
Endogenous IGF-1 is a peptide growth factor involved in a complex biological system that includes IGF receptors and multiple IGF-binding proteins.
Modified Analog
Long R3 IGF-1
IGF-1 LR3 incorporates an arginine substitution at the third position and an N-terminal extension, creating a modified research analog with altered binding-protein interactions.
IGF-1 Receptor Signaling Research
A major area of IGF-1 LR3 research centers on the IGF-1 receptor (IGF1R).
IGF1R is a receptor tyrosine kinase. Ligand binding can initiate intracellular signaling networks that researchers investigate in relation to cellular growth, survival, differentiation and metabolism.
Two frequently investigated downstream signaling systems are the PI3K/AKT and MAPK/ERK pathways. These pathways participate in broad cellular signaling networks and are studied across many experimental models.
IGF1R
Investigation of IGF-1 receptor binding and activation.
PI3K / AKT
Research involving intracellular metabolic and cellular
signaling pathways.
MAPK / ERK
Investigation of signaling associated with cellular responses
to growth factors.
Cellular Growth & Differentiation Research
Growth factors are important experimental tools for investigating how extracellular signals influence cellular behavior.
IGF-associated signaling has therefore been studied in laboratory models examining cell proliferation, differentiation, protein synthesis, survival signaling and cellular metabolism.
IGF-1 LR3 provides researchers with a modified IGF analog for investigating these pathways while separately characterizing the effects of its altered molecular structure.
Metabolic Signaling Research
The IGF signaling network intersects with several pathways involved in cellular nutrient sensing and metabolic regulation.
Experimental research can therefore use IGF-1 LR3 to examine relationships among growth-factor signaling, glucose metabolism, amino-acid signaling, protein synthesis and cellular energy pathways.
These are mechanistic research areas and should not be interpreted as evidence of a therapeutic effect from IGF-1 LR3.
IGF-1 LR3 Research Areas
Growth-Factor Biology
Investigation of signaling initiated by growth-factor receptor
systems.
IGF1R Signaling
Experimental characterization of IGF-1 receptor activity.
Cellular Proliferation
Laboratory investigation of growth-associated cellular
signaling.
Cell Differentiation
Research into signaling associated with changes in cellular
state and phenotype.
Protein Synthesis
Investigation of signaling pathways involved in cellular
protein regulation.
Metabolic Biology
Study of interactions between growth-factor and metabolic
signaling networks.
IGF-1 LR3 1mg Research Specifications
Compound
IGF-1 LR3
Content
1mg
Alternative Name
Long R3 IGF-1
Compound Type
Modified IGF-1 Analog
Primary Research Target
IGF-1 Receptor (IGF1R)
Research Category
Growth-Factor Signaling
Why Is Long R3 IGF-1 Studied?
Long R3 IGF-1 is scientifically interesting because it combines recognizable IGF-1 receptor activity with structural modifications that distinguish it from endogenous IGF-1.
Researchers can therefore use the molecule to investigate both IGF receptor signaling and how structural changes to a growth-factor analog influence its biochemical interactions.
This has made IGF-1 LR3 a recurring experimental compound in studies involving growth-factor biology, receptor signaling and cellular metabolism.
IGF-1 LR3 1mg FAQ
What is IGF-1 LR3?
IGF-1 LR3, or Long R3 IGF-1, is a structurally modified analog of insulin-like growth factor 1 used in laboratory research involving IGF receptor signaling and growth-factor biology.
What does LR3 mean in IGF-1 LR3?
LR3 refers to Long R3. The analog contains an arginine substitution at position three along with an N-terminal peptide extension relative to native IGF-1.
Is IGF-1 LR3 the same as native IGF-1?
No. IGF-1 LR3 is a modified analog of IGF-1 and has structural differences that alter aspects of its biochemical behavior, including interactions with IGF-binding proteins.
What receptor is associated with IGF-1 LR3 research?
A primary research target is the insulin-like growth factor 1 receptor, commonly abbreviated IGF1R.
What pathways are investigated in IGF-1 research?
IGF-associated research frequently examines downstream signaling systems including PI3K/AKT and MAPK/ERK, along with broader cellular growth and metabolic signaling networks.
What is the strength of this IGF-1 LR3 product?
This research product contains 1mg of IGF-1 LR3 per vial.
Is IGF-1 LR3 1mg intended for human use?
No. This material is supplied strictly for laboratory and research purposes and is not intended for human or veterinary use.
For Research Use Only
IGF-1 LR3 1mg is supplied strictly for laboratory, analytical and
research purposes. It is not intended for human or veterinary use,
consumption, diagnosis, treatment, prevention or mitigation of
disease. References to growth, metabolism, protein synthesis,
cellular proliferation or other biological processes describe
mechanisms and areas of scientific investigation and do not
constitute therapeutic or performance claims.
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ProductIGF-1 LR3 1mg
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